Target General Information
Target ID T46456
Target Name Retinoic acid receptor RXR-gamma
Synonyms Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma; RXRG
Target Type Successful
Gene Name RXRG
Biochemical Class Nuclear hormone receptor
UniProt ID RXRG_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Prostate cancer
Example drug IRX4204 Phase 1 [525182], [1572592]
Tissue Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.25
Z-score: -0.41
P-value: 4.44E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 525182ClinicalTrials.gov (NCT02438215) Study of IRX4204 for Treatment of Early Parkinson's Disease. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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