Target General Information
Target ID T48940
Target Name HIF prolyl hydroxylase
Target Type Successful
Gene Name EGLN2
Biochemical Class Oxidoreductases (EC:1)
UniProt ID EGLN2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Anemia
Example drug FG-2216 Phase 2 [547665], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 4.40E-03
Z-score: 0.02
P-value: 7.70E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 547665Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018242)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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