Target General Information
Target ID	T49630
Target Name	Lectin-like oxidized ldl receptor
Synonyms	LOX-1; LOX1; Lectin-like oxidized LDL receptor-1; Lectin-like oxidized low-density lipoprotein receptor-1; Lectin-type oxidized LDL receptor; Oxidised low density lipoprotein (Lectin-like) receptor 1; Oxidized low-density lipoprotein receptor; OLR1
Target Type	Discontinued
Gene Name	OLR1
Biochemical Class	Transmembrane protein
UniProt ID	OLR1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Arteriosclerosis
Example drug	RG7418			Discontinued in Phase 1	[1], [2]
Tissue	Peripheral blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.08 Z-score: -0.35 P-value: 3.35E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019399)
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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