Target General Information
Target ID	T50444
Target Name	Connective tissue growth factor
Synonyms	CCN2; Hypertrophic chondrocyte-specific protein 24; Long; CTGF
Target Type	Clinical Trial
Gene Name	CTGF
Biochemical Class	CCN intercellular signaling protein
UniProt ID	CTGF_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Idiopathic pulmonary fibrosis
Example drug	FG-3019			Phase 2	[1], [2]
Tissue	Lung tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.79 Z-score: -0.83 P-value: 2.36E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Disease	Type 2 diabetes
Example drug	FG-3019			Phase 2	[1], [2]
Tissue	Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.03 Z-score: 0.12 P-value: 5.03E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	Agents in development for the treatment of diabetic nephropathy. Expert Opin Emerg Drugs. 2008 Sep;13(3):447-63.
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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