Target expression details
Target General Information | |||||
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Target ID | T51499 | ||||
Target Name | Ganglioside GM2 activator | ||||
Synonyms | Cerebroside sulfate activator protein; GM2AP; Ganglioside GM2 activator isoform short; SAP3; Sphingolipid activator protein 3; GM2A | ||||
Target Type | Clinical Trial | ||||
Gene Name | GM2A | ||||
UniProt ID | SAP3_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Myeloma | ||||
Example drug | BIW-8962 | Phase 1/2 | [1], [2] | ||
Tissue | Bone marrow | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.20 Z-score: 0.40 P-value: 1.75E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | ClinicalTrials.gov (NCT01898156) Two-Part, Open-Label, Multi-Center, Phase 1/2 Study of BIW-8962 as Monotherapy in Subjects With Lung Cancer. U.S. National Institutes of Health. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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