Target General Information
Target ID T54761
Target Name Myelin basic protein
Synonyms Myelin A1 protein; Myelin membrane encephalitogenic protein; MBP
Target Type Clinical Trial
Gene Name MBP
Biochemical Class Myelin basic protein
UniProt ID MBP_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Multiple sclerosis
Example drug BHT-3009 Phase 2 [521894], [1572592]
Tissue Spinal cord
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: 0.02
Z-score: 0.18
P-value: 7.10E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 521894ClinicalTrials.gov (NCT00382629) BHT-3009 Immunotherapy in Relapsing Remitting Multiple Sclerosis. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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