Target General Information
Target ID T55285
Target Name Glycine receptor
Synonyms GLR; Glycine receptor 58 kDa subunit; GLRB
Target Type Successful
Gene Name GLRB
Biochemical Class Neurotransmitter receptor
UniProt ID GLRB_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Epilepsy
Example drug MDL-27531 Phase 1 [526961], [1572592]
Tissue Peritumoral cortex tissue
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 526961MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord. Neurosci Lett. 1992 Nov 23;147(1):101-5.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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