Target expression details
Target General Information | |||||
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Target ID | T55860 | ||||
Target Name | OX40 ligand | ||||
Synonyms | CD252; Glycoprotein Gp34; OX40L; TAX transcriptionally-activated glycoprotein 1; Tumor necrosis factor ligand superfamily member 4; TNFSF4 | ||||
Target Type | Clinical Trial | ||||
Gene Name | TNFSF4 | ||||
Biochemical Class | Cytokine: tumor necrosis factor | ||||
UniProt ID | TNFL4_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | R4930 | Discontinued in Phase 2 | [1], [2] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.12 Z-score: -0.21 P-value: 9.04E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027884) | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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