Target General Information
Target ID T57011
Target Name mRNA of ICAM1
Synonyms CD54 antigen; ICAM-1; Major group rhinovirus receptor; ICAM1
Target Type Successful
Gene Name ICAM1
Biochemical Class Target of antisense drug
UniProt ID ICAM1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Ulcerative colitis
Example drug Alicaforsen Phase 2 [551048], [1572592]
Tissue Colon mucosal tissue
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: 0.26
Z-score: 0.30
P-value: 1.04E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 551048Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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