Target General Information
Target ID T57718
Target Name Melanoma-associated antigen C2
Synonyms CT10; Cancer/testis antigen 10; Hepatocellular carcinomaassociated antigen 587; MAGEC2 antigen; MAGEE1 antigen; MAGEC2
Target Type Clinical Trial
Gene Name MAGEC2
Biochemical Class Melanoma associated antigen family
UniProt ID MAGC2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Lung cancer
Example drug CV-9201 Phase 1/2 [522696], [1572592]
Tissue Lung tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.08
Z-score: 0.43
P-value: 1.99E-21
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -1.70E-03
Z-score: -0.01
P-value: 1.36E-10
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 522696ClinicalTrials.gov (NCT00923312) Trial of an RNActive-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC). U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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