Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T59604 | ||||
| Target Name | Growth hormone secretagogue receptor type 1 | ||||
| Synonyms | GH-releasing peptide receptor; GHRP; GHS-R; Ghrelin receptor; Growth hormone secretagogue receptor; GHSR | ||||
| Target Type | Successful | ||||
| Gene Name | GHSR | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | GHSR_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Type 2 diabetes | ||||
| Example drug | PF-05190457 | Phase 1 | [523786], [1572592] | ||
| Tissue | Liver tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.14 Z-score: -0.74 P-value: 4.56E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Eosinophilic gastritis | ||||
| Tissue | Gastric antrum tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: 0.34 Z-score: 2.10 P-value: 4.45E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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