TTD | Expression Details

Target General Information
Target ID	T60606
Target Name	Thyrotropin receptor
Synonyms	TSH receptor; TSH-R; Thyroid stimulating hormone receptor; TSHR
Target Type	Successful
Gene Name	TSHR
Biochemical Class	GPCR rhodopsin
UniProt ID	TSHR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Thyroid cancer
Example drug	Thyrotropin Alfa			Approved	[538556], [1572592]
Tissue	Thyroid
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.72 Z-score: -1.00 P-value: 9.30E-18
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: -0.50 Z-score: -1.36 P-value: 1.73E-15
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data of the patients in the normal section of the tissue adjacent to the disease section Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 538556	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020898.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.