Target General Information
Target ID	T61657
Target Name	Retinoic acid receptor beta
Synonyms	HBV-activated protein; RAR-beta; RAR-epsilon; RARB
Target Type	Clinical Trial
Gene Name	RARB
Biochemical Class	Nuclear hormone receptor
UniProt ID	RARB_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	Tamibarotene			Phase 2/3	[529087], [539714], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.05 Z-score: -0.21 P-value: 9.92E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 539714	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2648).
Ref 529087	Tamibarotene. Drugs Today (Barc). 2007 Aug;43(8):563-8.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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