Target General Information
Target ID T62306
Target Name Motilin receptor
Synonyms Gprotein coupled receptor 38; MLNR
Target Type Clinical Trial
Gene Name MLNR
Biochemical Class GPCR rhodopsin
UniProt ID MTLR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Irritable bowel syndrome
Example drug RWJ-68023 Phase 1 [548041], [1572592]
Tissue Rectal colon tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.06
Z-score: -0.27
P-value: 6.35E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Eosinophilic gastritis
Tissue Gastric antrum tissue
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -0.05
Z-score: -0.07
P-value: 9.10E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
Ref 548041Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021456)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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