Target General Information
Target ID T67063
Target Name Maxi K potassium channel
Synonyms Calcium activated potassium KCNMA1 (maxiK) channel; KCNMB4
Target Type Clinical Trial
Gene Name KCNMB4
Biochemical Class Calcium-activated potassium channel
UniProt ID KCMB4_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug NS-1619 Terminated [467609], [545014], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.26
Z-score: 0.41
P-value: 5.61E-07
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 545014Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001878)
Ref 467609(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4272).
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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