Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T67079 | ||||
| Target Name | Interleukin-9 | ||||
| Synonyms | IL-9; P40 cytokine; T-cell growth factor P40; IL9 | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | IL9 | ||||
| Biochemical Class | Cytokine: interleukin | ||||
| UniProt ID | IL9_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Asthma | ||||
| Example drug | MEDI-528 | Phase 2 | [522773], [889340], [889344], [889345], [889351], [1572592] | ||
| Tissue | Nasal and bronchial airway | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.03 Z-score: -0.09 P-value: 8.78E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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| Reference | |||||
| Ref 889340 | ClinicalTrials.gov (NCT00394654) A Study to Evaluate the Efficacy of MEDI-528 on Late Asthmatic Response With Atopic Asthma | ||||
| Ref 889344 | ClinicalTrials.gov (NCT00483041) A Study to Evaluate the Effect of a Single-Dose Intravenous Administration of MEDI-528 | ||||
| Ref 889345 | ClinicalTrials.gov (NCT00507130) A Study to Evaluate the Safety and Tolerability of the Administration of MEDI-528 When Administered in Multiple Doses to Adults With Mild Persistent Asthma | ||||
| Ref 889351 | ClinicalTrials.gov (NCT00590720) A Phase 2A Study to Evaluate the Safety and Effect on Exercise Challenge Testing of MEDI-528 in Adults With Asthma | ||||
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