Target General Information
Target ID	T67079
Target Name	Interleukin-9
Synonyms	IL-9; P40 cytokine; T-cell growth factor P40; IL9
Target Type	Clinical Trial
Gene Name	IL9
Biochemical Class	Cytokine: interleukin
UniProt ID	IL9_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	MEDI-528			Phase 2	[1], [2], [3], [4], [5], [6]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.03 Z-score: -0.09 P-value: 8.78E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	ClinicalTrials.gov (NCT00968669) A Study to Evaluate the Effectiveness and Safety of MEDI-528 in Adults. U.S. National Institutes of Health.
REF 2	ClinicalTrials.gov (NCT00394654) A Study to Evaluate the Efficacy of MEDI-528 on Late Asthmatic Response With Atopic Asthma
REF 3	ClinicalTrials.gov (NCT00483041) A Study to Evaluate the Effect of a Single-Dose Intravenous Administration of MEDI-528
REF 4	ClinicalTrials.gov (NCT00507130) A Study to Evaluate the Safety and Tolerability of the Administration of MEDI-528 When Administered in Multiple Doses to Adults With Mild Persistent Asthma
REF 5	ClinicalTrials.gov (NCT00590720) A Phase 2A Study to Evaluate the Safety and Effect on Exercise Challenge Testing of MEDI-528 in Adults With Asthma
REF 6	NCBI GEO: archive for functional genomics data sets--update.

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