Target General Information
Target ID	T67207
Target Name	Low affinity immunoglobulin epsilon Fc receptor
Synonyms	BLAST2; CD23; Ctype lectin domain family 4 member J; FcepsilonRII; Immunoglobulin Ebinding factor; Low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor soluble form; Lymphocyte IgE receptor; FCER2
Target Type	Clinical Trial
Gene Name	FCER2
Biochemical Class	Immunoglobulin
UniProt ID	FCER2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Acute myelocytic leukemia
Example drug	Lumiliximab			Phase 2	[1], [2]
Tissue	Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.10 Z-score: -0.23 P-value: 9.88E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	ClinicalTrials.gov (NCT00391066) Lumiliximab With Fludarabine, Cyclophosphamide, and Rituximab (FCR) Versus FCR Alone in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL). U.S. National Institutes of Health.
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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