Target General Information
Target ID	T67416
Target Name	Bifunctional aminoacyl-tRNA synthetase
Synonyms	Bifunctional aminoacyltRNA synthetase; Bifunctional glutamate/prolinetRNA ligase; Cell proliferationinducing gene 32 protein; GluRS; GlutamatylprolyltRNA synthetase; ProlinetRNA ligase; EPRS
Target Type	Clinical Trial
Gene Name	EPRS
Biochemical Class	Carbon-oxygen ligase
UniProt ID	SYEP_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Muscular atrophy
Example drug	HT-100			Phase 2	[525293], [1572592]
Tissue	Muscle tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.56 Z-score: -1.70 P-value: 1.16E-05
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 525293	ClinicalTrials.gov (NCT02525302) HT-100 Long-term Study in DMD Patients Who Completed HALO-DMD-02.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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