Target expression details
Target General Information | |||||
---|---|---|---|---|---|
Target ID | T67658 | ||||
Target Name | Glucose transporter type 4 | ||||
Synonyms | Glucose transporter type 4, insulin-responsive; Glut4 protein; SLC2A4 | ||||
Target Type | Clinical Trial | ||||
Gene Name | SLC2A4 | ||||
Biochemical Class | Major facilitator superfamily | ||||
UniProt ID | GTR4_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Type 2 diabetes | ||||
Example drug | DS-1150b | Phase 1 | [1], [2] | ||
Tissue | Liver tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.06 Z-score: -0.73 P-value: 3.68E-01 |
||||
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
![]() |
|||||
Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
![]() |
|||||
Reference | |||||
REF 1 | ClinicalTrials.gov (NCT02004678) Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DS-1150b in Healthy Subjects and Subjects With Type-2 Diabetes Mellitus. U.S. National Institutesof Health. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.