Target General Information
Target ID T67658
Target Name Glucose transporter type 4
Synonyms Glucose transporter type 4, insulin-responsive; Glut4 protein; SLC2A4
Target Type Clinical Trial
Gene Name SLC2A4
Biochemical Class Major facilitator superfamily
UniProt ID GTR4_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug DS-1150b Phase 1 [524558], [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.06
Z-score: -0.73
P-value: 3.68E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 524558ClinicalTrials.gov (NCT02004678) Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DS-1150b in Healthy Subjects and Subjects With Type-2 Diabetes Mellitus. U.S. National Institutesof Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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