Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T71377 | ||||
| Target Name | Interleukin-3 receptor | ||||
| Synonyms | CD123 antigen; IL-3R-alpha; IL3RA | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | IL3RA | ||||
| Biochemical Class | Cytokine receptor | ||||
| UniProt ID | IL3RA_HUMAN||IL3RB_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Acute myelocytic leukemia | ||||
| Example drug | CSL-362-AML | Phase 1 | [549073], [1572592] | ||
| Tissue | Bone marrow | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.98 Z-score: 2.64 P-value: 8.71E-54 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Osteoporosis | ||||
| Example drug | Daniplestim | Terminated | [546034], [1572592] | ||
| Tissue | Bone marrow | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -2.73E-03 Z-score: -0.02 P-value: 2.75E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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| Reference | |||||
| Ref 546034 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005988) | ||||
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