Target General Information
Target ID	T73724
Target Name	Neuronal ACh receptor beta-4
Synonyms	Beta-4 nAChR; CHRNB4
Target Type	Discontinued
Gene Name	CHRNB4
Biochemical Class	Ion transport
UniProt ID	ACHB4_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	SIB-1553A			Discontinued in Phase 2	[546683], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 9.66E-03 Z-score: 0.06 P-value: 8.30E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 546683	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009631)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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