Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T75797 | ||||
| Target Name | Prostaglandin F2-alpha receptor | ||||
| Synonyms | FP prostaglandin receptor; FP prostanoid receptor; PGF receptor; PGF2 alpha receptor; Prostanoid FP receptor; PTGFR | ||||
| Target Type | Successful | ||||
| Gene Name | PTGFR | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | PF2R_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Renal cancer | ||||
| Example drug | BOL-303259-X | Phase 3 | [524354], [1572592] | ||
| Tissue | Kidney | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.47 Z-score: -0.84 P-value: 2.69E-01 |
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| Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: -0.80 Z-score: -1.59 P-value: 1.15E-11 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
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| Disease | Alzheimer's disease | ||||
| Tissue | Entorhinal cortex | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.05 Z-score: -0.14 P-value: 8.25E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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