Target General Information
Target ID T78381
Target Name Interleukin-29
Synonyms Cytokine Zcyto21; IFNlambda1; IL29; Interferon lambda1; Interleukin29; IFNL1
Target Type Clinical Trial
Gene Name IFNL1
Biochemical Class Cytokine: interferon
UniProt ID IFNL1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Acute myelocytic leukemia
Example drug Peginterferon lambda-1a Phase 3 [524307], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.01
Z-score: -0.02
P-value: 4.97E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Reference
Ref 524307ClinicalTrials.gov (NCT01866930) Efficacy and Safety Study of Pegylated Interferon Lambda-1a With Ribavirin and Daclatasvir, to Treat naive Subjects With Chronic HCV Genotypes 1, 2, 3, and 4 Who Are Co-infected With HIV. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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