Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T78381 | ||||
| Target Name | Interleukin-29 | ||||
| Synonyms | Cytokine Zcyto21; IFNlambda1; IL29; Interferon lambda1; Interleukin29; IFNL1 | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | IFNL1 | ||||
| Biochemical Class | Cytokine: interferon | ||||
| UniProt ID | IFNL1_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Acute myelocytic leukemia | ||||
| Example drug | Peginterferon lambda-1a | Phase 3 | [1], [2] | ||
| Tissue | Bone marrow | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.01 Z-score: -0.02 P-value: 4.97E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Reference | |||||
| REF 1 | ClinicalTrials.gov (NCT01866930) Efficacy and Safety Study of Pegylated Interferon Lambda-1a With Ribavirin and Daclatasvir, to Treat naive Subjects With Chronic HCV Genotypes 1, 2, 3, and 4 Who Are Co-infected With HIV. U.S. National Institutes of Health. | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. | ||||
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