Target expression details
Target General Information | |||||
---|---|---|---|---|---|
Target ID | T78890 | ||||
Target Name | Tissue factor pathway inhibitor | ||||
Synonyms | EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; TFPI | ||||
Target Type | Clinical Trial | ||||
Gene Name | TFPI | ||||
UniProt ID | TFPI1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Sepsis | ||||
Example drug | Tifacogin | Phase 3 | [1], [2] | ||
Tissue | Whole blood | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.14 Z-score: 0.84 P-value: 1.27E-08 |
||||
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
![]() |
|||||
Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
![]() |
|||||
Reference | |||||
REF 1 | Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA. 2003 Jul 9;290(2):238-47. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.