Target General Information
Target ID	T79232
Target Name	Vasopressin V1a receptor
Synonyms	AVPR V1a; Antidiuretic hormone receptor 1a; V1a vasopressin receptor; V1aR; Vascular/hepatic-type arginine vasopressin receptor; AVPR1A
Target Type	Successful
Gene Name	AVPR1A
Biochemical Class	GPCR rhodopsin
UniProt ID	V1AR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Septic shock
Example drug	Selepressin			Phase 2	[523936], [1572592]
Tissue	Whole blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.12 Z-score: -0.34 P-value: 8.89E-04
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 523936	ClinicalTrials.gov (NCT01612676) Investigating FE 202158 as Potential Primary Treatment in Patients With Early Septic Shock. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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