Target General Information
Target ID T81100
Target Name mRNA of SLGT2
Synonyms mRNA of Low affinity sodium-glucose cotransporter; mRNA of Na(+)/glucose cotransporter 2; mRNA of SGLT2; mRNA of SLC5A2; mRNA of Sodium/glucosecotransporter 2; mRNA of Solute carrierfamily 5 member 2; SLC5A2
Target Type Clinical Trial
Gene Name SLC5A2
Biochemical Class Solute:sodium symporter
UniProt ID SC5A2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug ISIS-SGLT2 Phase 1 [551052], [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.09
Z-score: -0.37
P-value: 3.26E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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