Target General Information
Target ID	T82841
Target Name	Insulin
Synonyms	Insulin; Insulin A chain; INS
Target Type	Successful
Gene Name	INS
Biochemical Class	Insulin family
UniProt ID	INS_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Type 2 diabetes
Example drug	Insulin-detemir			Approved	[536361], [551186], [1572592]
Tissue	Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.12 Z-score: -0.46 P-value: 6.70E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 551186	2005 approvals: Safety first. Nature Reviews Drug Discovery 5, 92-93 (February 2006).
Ref 536361	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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