Target General Information
Target ID T83192
Target Name Ciliary neurotrophic factor
Synonyms CNTF
Target Type Clinical Trial
Gene Name CNTF
Biochemical Class Ciliary neurotrophic factor
UniProt ID CNTF_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Ovarian cancer
Example drug NT-501 CNTF Phase 1/2 [523988], [1572592]
Tissue Ovarian tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.29
Z-score: -0.70
P-value: 2.98E-01
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -0.13
Z-score: -0.69
P-value: 2.41E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 523988ClinicalTrials.gov (NCT01648452) CNTF Implants for CNGB3 Achromatopsia. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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