Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T83369 | ||||
| Target Name | Coagulation factor IX | ||||
| Synonyms | Christmas factor; Factor IX; PTC; Plasma thromboplastin component; F9 | ||||
| Target Type | Successful | ||||
| Gene Name | F9 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | FA9_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Coronary artery disease | ||||
| Example drug | RB-006 | Discontinued in Phase 3 | [547853], [1572592] | ||
| Tissue | Peripheral blood | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.13 Z-score: -0.45 P-value: 5.69E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Sepsis | ||||
| Example drug | SB 249417 | Discontinued in Phase 1 | [546894], [1572592] | ||
| Tissue | Whole blood | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.02 Z-score: -0.12 P-value: 3.59E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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| Reference | |||||
| Ref 546894 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010912) | ||||
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