Target General Information
Target ID T83376
Target Name Tumor suppressor candidate 2
Synonyms Fus-1 protein; Fusion 1 protein; PDGFA-associated protein 2; TUSC2
Target Type Clinical Trial
Gene Name TUSC2
Biochemical Class Tumour suppressor candidate 2
UniProt ID TUSC2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Lung cancer
Example drug CNVN-202 Phase 1/2 [547714], [1572592]
Tissue Lung tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.16
Z-score: -0.72
P-value: 3.62E-08
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -0.06
Z-score: -0.18
P-value: 8.13E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 547714Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018766)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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