Target General Information
Target ID T84631
Target Name Coagulation factor Xa
Synonyms Activated coagulation factor X; Factor Xa; Fxa; F10
Target Type Successful
Gene Name F10
Biochemical Class Peptidase
UniProt ID FA10_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Renal cancer
Example drug Human coagulation factor X BLA submitted [550389], [1572592]
Tissue Kidney
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.28
Z-score: -0.90
P-value: 4.84E-02
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -0.26
Z-score: -0.99
P-value: 2.78E-05
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 550389FDA Accepts BPL's Amended BLA Submission for Coagadex (Coagulation Factor X, Human). BPL Bio Products Laboratory USA, Inc.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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