Target General Information
Target ID	T85158
Target Name	Lymphotoxin alpha
Synonyms	LT-alpha; Lymphotoxin-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1; LTA
Target Type	Clinical Trial
Gene Name	LTA
Biochemical Class	Cytokine: tumor necrosis factor
UniProt ID	TNFB_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Rheumatoid arthritis
Example drug	Anti-LT alpha			Phase 2	[550794], [1572592]
Tissue	Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.19 Z-score: -0.92 P-value: 9.54E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 550794	Clinical pipeline report, company report or official report of Genentech (2011).
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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