Target General Information
Target ID	T85228
Target Name	mRNA of CCR3
Synonyms	CC CKR3 (mRNA); CC chemokine receptor type 3 (mRNA); CCCKR3 (mRNA); CCR3 (mRNA); CD193 (mRNA); CKR3 (mRNA); Eosinophil eotaxin receptor (mRNA); CCR3
Target Type	Clinical Trial
Gene Name	CCR3
Biochemical Class	Target of antisense drug
UniProt ID	CCR3_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	ASM8			Phase 2	[1], [2]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.01 Z-score: -0.04 P-value: 3.77E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	ClinicalTrials.gov (NCT01380236) A Single Blind Study to Evaluate the Safety, Tolerability and Explore the Efficacy of 8.0 mg ASM8 Inhaled Daily for 14 Days in Severe Asthma. U.S. National Institutesof Health.
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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