Target General Information
Target ID T85651
Target Name mRNA of MYC
Synonyms Class E basic helixloophelix protein 39 (mRNA); MYC (mRNA); Myc protooncogene protein (mRNA); Protooncogene cMyc(mRNA); Transcription factor p64 (mRNA); bHLHe39 (mRNA); MYC
Target Type Clinical Trial
Gene Name MYC
Biochemical Class Target of antisense drug
UniProt ID MYC_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Coronary artery disease
Example drug AVI-5126 Phase 2 [521992], [1572592]
Tissue Peripheral blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.25
Z-score: 0.37
P-value: 6.09E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 521992ClinicalTrials.gov (NCT00451256) Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG). U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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