Target expression details
Target General Information | |||||
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Target ID | T85651 | ||||
Target Name | mRNA of MYC | ||||
Synonyms | Class E basic helixloophelix protein 39 (mRNA); MYC (mRNA); Myc protooncogene protein (mRNA); Protooncogene cMyc(mRNA); Transcription factor p64 (mRNA); bHLHe39 (mRNA); MYC | ||||
Target Type | Clinical Trial | ||||
Gene Name | MYC | ||||
Biochemical Class | Target of antisense drug | ||||
UniProt ID | MYC_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Coronary artery disease | ||||
Example drug | AVI-5126 | Phase 2 | [1], [2] | ||
Tissue | Peripheral blood | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.25 Z-score: 0.37 P-value: 6.09E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | ClinicalTrials.gov (NCT00451256) Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG). U.S. National Institutes of Health. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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