Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T85857 | ||||
| Target Name | Thymic stromal lymphopoietin | ||||
| Synonyms | TSLP | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | TSLP | ||||
| UniProt ID | TSLP_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Asthma | ||||
| Example drug | MEDI9929 | Phase 2 | [1], [2] | ||
| Tissue | Nasal and bronchial airway | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.30 Z-score: 0.26 P-value: 8.89E-01 |
||||
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
|||||
| Reference | |||||
| REF 1 | ClinicalTrials.gov (NCT02054130) Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma. U.S. National Institutes of Health. | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.