Target General Information
Target ID T86014
Target Name Sphingosine kinase 1
Synonyms SK 1; SPK 1; SPHK1
Target Type Clinical Trial
Gene Name SPHK1
Biochemical Class Kinase
UniProt ID SPHK1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Arteriosclerosis
Example drug F-12509A Terminated [525833], [1572592]
Tissue Peripheral blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.01
Z-score: -0.06
P-value: 7.48E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 525833F-12509A, a new sphingosine kinase inhibitor, produced by a discomycete. J Antibiot (Tokyo). 2000 May;53(5):459-66.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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