Target General Information
Target ID	T86254
Target Name	Tenascin
Synonyms	Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Miotendinous antigen; Neuronectin; TN; TN-C; Tenascin-C; TNC
Target Type	Clinical Trial
Gene Name	TNC
Biochemical Class	Tenascin
UniProt ID	TENA_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Brain cancer
Example drug	131I-81C6			Terminated	[1], [2]
Tissue	Nervous tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 2.68 Z-score: 3.01 P-value: 2.41E-162
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	Human IgG2 constant region enhances in vivo stability of anti-tenascin antibody 81C6 compared with its murine parent. Clin Cancer Res. 1998 Oct;4(10):2495-502.
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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