Target General Information
Target ID T86273
Target Name G-protein coupled bile acid receptor 1
Synonyms BG37; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; M-BAR; Membrane-type receptor for bile acids; hBG37; hGPCR19; GPBAR1
Target Type Clinical Trial
Gene Name GPBAR1
Biochemical Class GPCR rhodopsin
UniProt ID GPBAR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug Sodium taurocholate Phase 1/2 [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.02
Z-score: 0.09
P-value: 4.60E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Reference
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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