Target General Information
Target ID	T86364
Target Name	Vasoactive intestinal polypeptide receptor 1
Synonyms	PACAP type II receptor; PACAP-R-2; Pituitary adenylate cyclase activating polypeptide type II receptor; VIP-R-1; VPAC-1; VPAC1; Vasoactive intestinal peptide receptor 1; Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor-1; VIPR1
Target Type	Clinical Trial
Gene Name	VIPR1
Biochemical Class	GPCR secretin
UniProt ID	VIPR1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Chronic obstructive pulmonary disease
Example drug	Vasoactive intestinal peptide			Phase 2	[522017], [1572592]
Tissue	Lung tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.16 Z-score: -0.14 P-value: 6.47E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Disease	Chronic obstructive pulmonary disease
Example drug	Vasoactive intestinal peptide			Phase 2	[522017], [1572592]
Tissue	Small airway epithelium
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.12 Z-score: -0.26 P-value: 4.24E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 522017	ClinicalTrials.gov (NCT00464932) Vasoactive Intestinal Peptide in COPD. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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