Target General Information
Target ID	T87749
Target Name	Growth/differentiation factor 8
Synonyms	GDF-8; Myostatin; MSTN
Target Type	Clinical Trial
Gene Name	MSTN
Biochemical Class	Growth factor
UniProt ID	GDF8_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Muscular atrophy
Example drug	AMG 745			Phase 2	[522779], [1572592]
Tissue	Muscle tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.06 Z-score: -0.06 P-value: 1.64E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 522779	ClinicalTrials.gov (NCT00975104) AMG 745 in Subjects With Age-associated Muscle Loss. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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