Target General Information
Target ID T90648
Target Name mRNA of B-Raf
Synonyms Proto-oncogene B-Raf (mRNA); Serine/threonine-protein kinase B-raf (mRNA); p94 (mRNA); v-Raf murine sarcoma viral oncogene homolog B1 (mRNA); BRAF
Target Type Clinical Trial
Gene Name BRAF
Biochemical Class Kinase
UniProt ID BRAF_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Parkinson's disease
Example drug SPN-803 Phase 1 [548872], [1572592]
Tissue Substantia nigra tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.23
Z-score: -0.43
P-value: 1.56E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 548872Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029757)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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