Target General Information
Target ID	T92030
Target Name	Human proislet peptide
Synonyms	HIP/PAP; Hepatointestinal pancreatic protein; Human proislet peptide; Pancreatitis-associated protein 1; REG-3-alpha; Reg III-alpha; Regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein 3-alpha 15 kDa form; Regenerating islet-derived protein III-alpha; REG3A
Target Type	Clinical Trial
Gene Name	REG3A
Biochemical Class	Regiii family
UniProt ID	REG3A_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Liver failure
Example drug	ALF-5755			Phase 2	[523402], [1572592]
Tissue	Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.13 Z-score: -0.87 P-value: 1.68E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 523402	ClinicalTrials.gov (NCT01318525) Efficacy & Safety of ALF-5755 in Patients With Nonacetaminophen Severe Acute Hepatitis & Early Stage Acute Liver Failure. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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