Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T92124 | ||||
| Target Name | Tumor necrosis factor receptor 4 | ||||
| Synonyms | ACT35 antigen; CD134 antigen; Cell surface receptor OX40; OX40 antigen; OX40L receptor; TAX-transcriptionally activated glycoprotein 1 receptor; TNFRSF4 | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | TNFRSF4 | ||||
| Biochemical Class | Transmembrane protein | ||||
| UniProt ID | TNR4_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Prostate cancer | ||||
| Example drug | Anti-OX40 mab | Phase 1 | [532531], [1572592] | ||
| Tissue | Prostate | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 1.01 Z-score: 1.66 P-value: 2.17E-06 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Asthma | ||||
| Tissue | Nasal and bronchial airway | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.08 Z-score: -0.10 P-value: 1.87E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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