Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T92144 | ||||
| Target Name | Angiopoietin-1 receptor | ||||
| Synonyms | CD202b antigen; Endothelial Cell-Specific Receptor TIE-2; P140 TEK; Tunica interna endothelial cell kinase; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; TEK | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | TEK | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | TIE2_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Myelodysplastic syndromes | ||||
| Example drug | ARRY-614 | Discontinued in Phase 1 | [548520], [1572592] | ||
| Tissue | Bone marrow | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.29 Z-score: 0.84 P-value: 4.92E-03 |
||||
| Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: 0.58 Z-score: 12.78 P-value: 1.26E-14 |
||||
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
|
|||||
| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
|
|||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.