TTD | Expression Details

Target General Information
Target ID	T94482
Target Name	Interleukin-20
Synonyms	Four alpha helix cytokine ZCYTO10; IL-20; UNQ852/PRO1801; IL20
Target Type	Clinical Trial
Gene Name	IL20
Biochemical Class	Cytokine: interleukin
UniProt ID	IL20_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Psoriasis
Example drug	NN-8226			Phase 2	[524692], [1572592]
Tissue	Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 1.01 Z-score: 1.18 P-value: 1.82E-12
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: 1.79 Z-score: 7.42 P-value: 3.31E-85
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data of the patients in the normal section of the tissue adjacent to the disease section Download target gene expression data in the tissue of healthy individual
Reference
Ref 524692	ClinicalTrials.gov (NCT02097264) A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.