Target General Information
Target ID T97873
Target Name C-C chemokine receptor type 9
Synonyms CC CKR9; CC chemokine receptor type 9; CCCKR9; CDw199; GPR96; Gprotein coupled receptor 28; CCR9
Target Type Clinical Trial
Gene Name CCR9
Biochemical Class GPCR rhodopsin
UniProt ID CCR9_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Sjogren's syndrome
Example drug MLN-3126 Phase 1 [524863], [1572592]
Tissue Salivary gland tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.02
Z-score: 0.22
P-value: 7.74E-01
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -0.20
Z-score: -1.45
P-value: 2.31E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 524863ClinicalTrials.gov (NCT02209506) Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MLN3126 in Healthy Japanese and Non-Japanese Participants. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.