Target General Information
Target ID	T98052
Target Name	SLAM family member 7
Synonyms	CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CD319; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; SLAMF7
Target Type	Clinical Trial
Gene Name	SLAMF7
Biochemical Class	Immunoglobulin
UniProt ID	SLAF7_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Myeloma
Example drug	Elotuzumab			Phase 3	[523429], [543087], [1572592]
Tissue	Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.13 Z-score: 0.31 P-value: 9.74E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 543087	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8361).
Ref 523429	ClinicalTrials.gov (NCT01335399) Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma. U.S. National Institutesof Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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