Target expression details
Target General Information | |||||
---|---|---|---|---|---|
Target ID | T99948 | ||||
Target Name | Programmed death ligand PD-L1 | ||||
Synonyms | B7 homolog 1; B7H1; PDCD1 ligand 1; PDL1; Programmed cell death 1 ligand 1; Programmed death ligand 1; CD274 | ||||
Target Type | Successful | ||||
Gene Name | CD274 | ||||
Biochemical Class | Immunoglobulin | ||||
UniProt ID | PD1L1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Bladder cancer | ||||
Example drug | RG-7446 | Phase 3 | [1], [2] | ||
Tissue | Bladder tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.37 Z-score: 2.10 P-value: 4.38E-07 |
||||
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
![]() |
|||||
Reference | |||||
REF 1 | 2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76. doi: 10.1038/nrd.2017.14. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.