Target General Information
Target ID	T99948
Target Name	Programmed death ligand PD-L1
Synonyms	B7 homolog 1; B7H1; PDCD1 ligand 1; PDL1; Programmed cell death 1 ligand 1; Programmed death ligand 1; CD274
Target Type	Successful
Gene Name	CD274
Biochemical Class	Immunoglobulin
UniProt ID	PD1L1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Bladder cancer
Example drug	RG-7446			Phase 3	[889440], [1572592]
Tissue	Bladder tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.37 Z-score: 2.10 P-value: 4.38E-07
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Reference
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.
Ref 889440	2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76. doi: 10.1038/nrd.2017.14.

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