Target Information

Target General Infomation
Target ID
T07374
Former ID
TTDI02128
Target Name
Beta microseminoprotein
Gene Name
MSMB
Synonyms
Betamicroseminoprotein; IGBF; Immunoglobulinbinding factor; PN44; PSP94; Prostate secreted seminal plasma protein; Prostate secretory protein of 94 amino acids; Seminal plasma betainhibin; MSMB
Target Type
Clinical Trial
Disease Hormone refractory prostate cancer [ICD9: 140-229, 185; ICD10: C61]
BioChemical Class
Beta-microseminoprotein
UniProt ID
P08118
Sequence
MNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETC
TCYETEISCCTLVSTPVGYDKDNCQRIFKKEDCKYIVVEKKDPKKTCSVSEWII
Drugs and Mode of Action
Drug(s) Tigapotide Drug Info Phase 1 Hormone refractory prostate cancer [522345]
Inhibitor Tigapotide Drug Info [550431]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
TEP EXP Info
References
Ref 522345ClinicalTrials.gov (NCT00695851) Dose-Seeking Trial of PCK3145 in Asymptomatic, Castrate Metastatic Prostate Cancer Patients.. U.S. National Institutes of Health.
Ref 550431National Cancer Institute Drug Dictionary (drug id 600185).

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