Target Information

Target General Infomation
Target ID
T54931
Former ID
TTDR00195
Target Name
Nicotinic acetylcholine receptoralpha2 / alpha3
Target Type
Research
Disease Drug abuse [ICD9: 303-304; ICD10: F10-F19]
UniProt ID
Q15822||P32297
Antagonist 18-Methoxycoronaridine Drug Info [535412]
Ibogaine Drug Info [535412]
Laudanosine Drug Info [535185]
Volatile anesthetics Drug Info [535371]
Agonist SIB-1533A Drug Info [535007]
References
Ref 535007Nicotine, brain nicotinic receptors, and neuropsychiatric disorders. Arch Med Res. 2000 Mar-Apr;31(2):131-44.
Ref 535185Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine. Anesthesiology. 2001 Apr;94(4):643-51.
Ref 535371The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia. Brain Res Bull. 2002 Jan 15;57(2):133-50.
Ref 535412Antagonism of alpha 3 beta 4 nicotinic receptors as a strategy to reduce opioid and stimulant self-administration. Eur J Pharmacol. 2002 Mar 1;438(1-2):99-105.

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